Hi I have 3 year old male lab.When I had brought a lab vet had given him Cannine Distemper-Adenovirus Type 2 Parainfluenza Parvovirus Vaccine in the year August 2015.After this vet had told me to come after one year for revaccination in the year 2016 but at that time he was having ticks & fleas on him so the vaccination got delayed for few months.Last year he was having skin infection and again the vaccination got delayed.Now he got fits / seizures thrice in last 6 months and Vet has prescribed gardinal 30mg twice a day for 1 year.Now I am worried & i want to know if my boy Rocky is getting fits / seizures because the vet has delayed the vaccines and is this Cannine Distemper-Adenovirus Type 2 Parainfluenza Parvovirus Vaccine is to be given complusory to labs every year.
Hi Raj, Sorry to hear you are having problems with your boy. There are many causes for seizures, and sometimes we think medication or vaccines might have been the cause, but in most cases there is an underlying tendency unrelated to medication. Sometimes vaccines, or flea treatments, or stress can be the trigger for a seizure. It is very difficult to prove one way or the other. I had a quick google and couldn't find a data sheet for this vaccine that mentioned and possible side-effects. Have you spoken to your vet? What have they said?
By compulsory do you mean legal? Where I live it is not. Here where I am in Canada only Rabies is legally required by law. Day care, boarding and training facilities may make their own stipulations as to what vaccinations they want dogs visiting or staying with them to have. The DHPP my dog got is good for three years. I titred after three years, protective levels were still high and I did not re-vaccinate. You are lucky to have a Vet who would not vaccinate an unhealthy dog. Speak to your Vet. It is true that vaccinosis, a symptom of which may be seizures, is thought to be linked to many vaccines. As said above, more data needs to be collected. I have never heard of seizures being supposed to be related to not keeping vaccines up.
The only thing a dog (or human....) can "get" from not having a vaccination, is the illness that a vaccination is preventing. So while seizures could be triggered by a vaccine sude effect, they wont be triggered by not having the vaccine - except in case if an immunizeable disease that seizures are a symptom of.
Some good reading here: https://healthypets.mercola.com/sit...t&utm_campaign=20180601_pets-over-vaccination
I’m sorry, but what? No. Just no. Look, I’m not pro vaccinating for everything every year. I have to do it because where I live, it’s the law. Given the choice, I would titre test and only vaccinate when it was necessary. But this article is so full of sensationalist bull crap, it’s not even funny. Let’s gloss over the lack of citations, the fact it’s clearly self serving and full of scaremongering that even someone who is vaguely sympathetic to the cause can see. But this?? “I personally know people who've adopted or purchased a puppy and had the pup die of anaphylactic shock on the exam table at the first vet visit immediately after receiving a vaccination.” What? WHAT?! This is a vet who had been practicing for 30 years who says that puppies suffered anaphylactic shock after their first injections? That is not possible!!! Systemic responses happen after previous exposure and CANNOT happen on first exposure. Sorry, I can get on board with not wanting to over-vaccinate but this is an article straight from the table of the anti-vaxxers and should be vilified as dangerous and inaccurate. They say they’re not anti-vaxxers, though, so that makes me wrong, right? “What Dr. Robb and I are talking about is the danger of over-vaccinating dogs and cats.” Yet they just said, at the first visit, puppies died from anaphylaxis following vaccination. How is that over-vaccination if it’s their first? No, this is nothing more than sensationalist “journalism”, preying on people’s emotions. I call baloney. People that aren’t familiar with Joseph Mercola might not realise that he’s simply another charlatan selling his own brand of snake oil, but just because the person in the picture is wearing a white coat doesn’t mean they’re a trustworthy source of information. This site has its own agenda and that’s making money from people’s fears. Fears that they have done a wonderful job in fostering.
I'm trying to look this up. I can't find anything, so far, to confirm anaphylaxis is not possible on the first injection, as you claim. Or that it can happen. Can you provide links on this?
https://www.emedicinehealth.com/sev...cle_em.htm#what_is_a_severe_allergic_reaction For an anaphylactic reaction to occur, you must have been exposed in the past to the substance that causes the reaction, called the antigen. This is called "sensitization." A bee sting, for example, may not cause an allergic reaction the first time. Another bee sting may produce a sudden, severe allergic reaction known as anaphylaxis or anaphylactic shock. https://patient.info/health/allergies An allergen is regarded by the immune system as a foreign substance. When the immune system detects an allergen, it produces an immune system protein called an antibody. Antibodies are also called immunoglobulins. An immunoglobulin commonly involved is called IgE. The immune system stores this in its memory (this is called sensitisation). This means that you do not have an allergic reaction the first time you come into contact with a specific allergen. https://www.medicinenet.com/anaphylaxis/article.htm#what_is_the_history_of_anaphylaxis Although it may appear that IgE-mediated anaphylaxis occurs upon a first exposure to a food, drug, or insect sting, there must have been a prior sensitization from a previous exposure, which is often unknown. ETA It’s noteworthy that you can have something like an anaphylactic reaction on first exposure (called an “anaphylactoid reaction”) but that is not anaphylaxis which is what the person in this article is claiming.
That is all brand new information to me, amazing. I got a bee sting this summer for the first time. I was relieved to find out that I wasn't allergic, but it turns out that I won't know I'm allergic until (if) I get stung again? Very helpful, thank you.
https://www.anaphylaxis.org.uk/hcp/what-is-anaphylaxis/signs-and-symptoms/ This is a good site for info. I was stung when I was around 10 when I sat on a bee casually loitering on our toilet seat. . Have been stung since on the foot without further issues, thankfully.
I have since found other sites mentionning anaphylactic shock on first exposure. Perhaps the degree of the first reaction is what needs to be defined. Or, perhaps in some cases, bee sting, a first exposure went unnoticed.
Ermmmm.....not really, but hey, having lunch browsing and will keep me from housework It's all got to do with Type1 or Type2 sensitivity and the involvement of Immunoglobulin E (IgE) in the mast cells which are activated by the allergen. SOMETHING has to sensitize them first. There are some cross-over issues, such as banana (or is it Kiwi?) and Latex, so one can sensitize for contact with the other in susceptible people. And I guess maternal exposure to a substance in utero could potentially act as an index exposure. So the allergen, whatever it may be, needs to be swallowed by good white cells, which then builds a set of antibodies (including the the IgE) to defend itself from further "attack", and sticks the IgE receptors to other white cells in the defence armament of the body. At a second exposure (or third, fourth etc) these receptors will mount an attack on the allergen, but typical that the body over-reacts and produces so much of a defence that there is oodles of histamine and other chemicals released that cause all the typical allergic reaction of hives, spasm of the lungs, swollen tongue, widening of blood vessels, low blood pressure etc. With the anyphylactoid reaction, you don't need a prior sensitisation, the generic mast cell receptors that start this off are usually a different Immunoglobulin (IgG or sometimes IgM I think) although the effects with release of chemicals and histamine from the mast cells can be similar, but normally not quite so overwhelming. So anaphylactic reactions are always IgE mediated, but anaphylactoid reactions are "non-IgE mediated". You need something to sensitize you to get the IgE being made in the first place. I shall stop now........sorry for all the guff.
That's far more convincing coming from an actual medical doctor than from me - or Dr Google! Thanks Jac!
I am always concerned when I read articles against vaccination and sometimes that 'vets do it only for the money'! I have seen dogs die of distemper, parvovirus, leptospirosis and am very grateful that there are now vaccines.
My vet friend says the same she never seen a bad reaction to vaccination but has seen plenty of dogs/puppies die from lack of vaccination. She vaccinates her own dogs so that's good enough for me.
What great replies and explanations from Fiona and Jac. Thank you so much for taking the time to post them. The only bit I disagree with is this It is my biggest bugbear with so many so called medical or expert sites. It simply isn't acceptable to set out medical advice or information without giving any clue as to where the relevant data can be found.
